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  2. HIV prevalence in Tanzania is still high at 4.7% among adults. Regular HIV testing is consistently advocated in the country to increase the level of awareness of HIV status, thus contributing to national HIV p...

    Authors: Ramadhani Abdul, Tobias F. Rinke de Wit, Giulia Martelli, Kathleen Costigan, Patrobas Katambi, Peter Mllacha, Anton Pozniak, Werner Maokola, Sayoki Mfinanga and Sabine Hermans
    Citation: AIDS Research and Therapy 2023 20:44
    Content type: Research Published on:

  3. Pre-Exposure Prophylaxis (PrEP) has demonstrated clinical efficacy in preventing HIV infection, yet its uptake remains low. This study, conducted in five PrEP implementing districts in Lesotho, examined factor...

    Authors: Joy J. Chebet, Shannon A. McMahon, Tapiwa Tarumbiswa, Hlalele Hlalele, Chivimbiso Maponga, Esther Mandara, Kacey Ernst, Halimatou Alaofe, Till Baernighausen, John E. Ehiri, Pascal Geldsetzer and Mark Nichter
    Citation: AIDS Research and Therapy 2023 20:43
    Content type: Research Published on:

  4. Poor adherence and under-utilization of antiretroviral therapy (ART) services have been major setbacks to achieving 95-95-95 policy goals in Sub-Saharan Africa. Social support and mental health challenges may ...

    Authors: Jerry John Nutor, Akua O. Gyamerah, Robert Kaba Alhassan, Henry Ofori Duah, Rachel G.A. Thompson, Natalie Wilson, Orlando Harris, Jose Gutierrez, Thomas J. Hoffmann, Monica Getahun and Glenn-Milo Santos
    Citation: AIDS Research and Therapy 2023 20:42
    Content type: Research Published on:

  5. This retrospective study aimed to characterize the distribution of HIV-1 genotypes and the prevalence of drug resistance mutations in people with antiretroviral treatment (ART) failure in Suzhou City, China.

    Authors: Zefeng Dong, Zhihui Xu, Ying Zhou, Runfang Tian, Kai Zhou, Di Wang, Xuerong Ya and Qiang Shen
    Citation: AIDS Research and Therapy 2023 20:41
    Content type: Research Published on:

  6. Within the African region, there are an estimated 8 million people living with HIV (PLHIV) in South Africa. Seeking healthcare services from traditional healers (TH) is one of the alternative and complementary...

    Authors: Joshua Okyere, Castro Ayebeng, Bernard Afriyie Owusu, Wonder Agbemavi, Joseph Kwarteng Amoako and Kwamena Sekyi Dickson
    Citation: AIDS Research and Therapy 2023 20:40
    Content type: Research Published on:

  7. In 2016 the WHO declared HIV self-testing and self-sampling an effective and safe test option that can reduce testing barriers. HIV self-tests and self-sampling kits (HIVST/HIVSS) are available for purchase at...

    Authors: Chaima Kandil, Jacqueline Hugtenburg, Titia Heijman, Hanna Bos, Martina Teichert, Renee Finkenflügel and Eline Op de Coul
    Citation: AIDS Research and Therapy 2023 20:39
    Content type: Research Published on:

  8. The patients’ perception of the health service is a vital tool for measuring health service quality. Besides, Patient satisfaction is an essential feature in assessing the quality of health services. Health in...

    Authors: Tafere Mulaw Belete, Solomon Asmamaw Tadesse, Kidist Atnafu, Minilik Kelemu and Assefa Belay Asrie
    Citation: AIDS Research and Therapy 2023 20:38
    Content type: Research Published on:

  9. Antiretroviral therapy (ART) is very effective in preventing vertical transmission of HIV but some women on ART experience different virologic, immunologic, and safety profiles. While most pregnant women are c...

    Authors: Maganizo B. Chagomerana, Bryna J. Harrington, Bethany L. DiPrete, Shaphil Wallie, Madalitso Maliwichi, Austin Wesevich, Jacob N. Phulusa, Wiza Kumwenda, Allan Jumbe and Mina C. Hosseinipour
    Citation: AIDS Research and Therapy 2023 20:37
    Content type: Research Published on:

  10. Concerns about the interconnected relationship between HIV and mental health were heightened during the COVID-19 pandemic. This study assessed whether there were temporal changes in the mental health status of...

    Authors: Solis Winters, Amon Sabasaba, Carolyn A. Fahey, Laura Packel, Emmanuel Katabaro, Yudas Ndungile, Prosper F. Njau and Sandra I. McCoy
    Citation: AIDS Research and Therapy 2023 20:36
    Content type: Research Published on:

  11. Effective antiretroviral therapy (ART) in people living with HIV (PLWH) has improved life expectancy and increased risk of age-associated cardiometabolic comorbidities. At-risk alcohol use is more frequent amo...

    Authors: Liz Simon, Stefany D. Primeaux, Danielle E. Levitt, Brianna Bourgeois, Neil M. Johannsen, Adrianna Peters, Jameel Ahmed, Richard H. Marshall, Alexandra H. Fairchild, Tekeda F. Ferguson and Patricia E. Molina
    Citation: AIDS Research and Therapy 2023 20:35
    Content type: Methodology Published on:

  12. The mental health and medical follow-up of people living with HIV (PLWH) have been disrupted by the COVID-19 pandemic. The objectives of this study were to assess anxiety, depression and substance use in Mexic...

    Authors: Ester Gutiérrez-Velilla, Vania Barrientos-Casarrubias, María Gómez-Palacio Schjetnan, Lydia E. Perrusquia-Ortiz, Rosa Cruz-Maycott, Claudia Alvarado-de la Barrera, Santiago Ávila-Ríos and Nancy Patricia Caballero-Suárez
    Citation: AIDS Research and Therapy 2023 20:34
    Content type: Research Published on:

  13. Discrete choice experiments (DCEs) are used to assess the strength of preferences and value of interventions. However, researchers using this approach have been criticized for not conducting or publishing rigo...

    Authors: Yihalem Abebe Belay, Mezgebu Yitayal, Asmamaw Atnafu and Fitalew Agimass Taye
    Citation: AIDS Research and Therapy 2023 20:33
    Content type: Research Published on:

  14. Pre-exposure prophylaxis (PrEP) is a proven biomedical strategy to prevent HIV transmission among men who have sex with men (MSM). Despite oral PrEP is safe and effective in MSM, the use of PrEP has been disco...

    Authors: Guang Zhang, Xue Yang, Wenting Kang, Tongtong Liu, Lili Cheng, Meixia Qu, Xinlun Wang and Houlin Tang
    Citation: AIDS Research and Therapy 2023 20:32
    Content type: Research Published on:

  15. Homosexual contact is the main route of human immunodeficiency virus type one (HIV-1) transmission in Cangzhou Prefecture, Hebei, China. Moreover, the number of circulating recombinant forms (CRFs) and unique ...

    Authors: Xinli Lu, Wenbin Gao, Yingying Wang, Meng Liu, Ning An, Yan Li, Yuqi Zhang and Qi Li
    Citation: AIDS Research and Therapy 2023 20:31
    Content type: Brief Report Published on:

  16. Gut damage allows translocation of bacterial lipopolysaccharide (LPS) and fungal β-D-glucan (BDG) into the blood. This microbial translocation contributes to systemic inflammation and risk of non-AIDS comorbid...

    Authors: Stéphane Isnard, Léna Royston, Susan C. Scott, Tsoarello Mabanga, John Lin, Brandon Fombuena, Simeng Bu, Carolina A. Berini, Mark S. Goldberg, Malcolm Finkelman, Marie-Josée Brouillette, Lesley K. Fellows, Nancy E. Mayo and Jean-Pierre Routy
    Citation: AIDS Research and Therapy 2023 20:30
    Content type: Research Published on:

  17. Polypharmacy, using five or more medications, may increase the risk of nonadherence to prescribed treatment. We aimed to identify the interrelationship between trajectories of adherence to antiretroviral thera...

    Authors: Abubaker Ibrahim Elbur, Musie Ghebremichael, Deborah Konkle-Parker, Deborah L Jones, Shelby Collins, Adaora A. Adimora, Michael F. Schneider, Mardge H. Cohen, Bani Tamraz, Michael Plankey, Tracey Wilson, Adebola Adedimeji, Jessica E. Haberer and Denise L. Jacobson
    Citation: AIDS Research and Therapy 2023 20:29
    Content type: Research Published on:

  18. Immune reconstitution inflammatory syndrome (IRIS) associated with syphilis has rarely been described in HIV-infected patients. Diagnosis can be challenging because it is not always possible to discern it from...

    Authors: Luca Pipitò, Alice Annalisa Medaglia, Marcello Trizzino, Silvia Bonura, Claudia Gioè, Paola Di Carlo, Claudia Colomba and Antonio Cascio
    Citation: AIDS Research and Therapy 2023 20:28
    Content type: Case Report Published on:

  19. COVID-19 has not only taken a staggering toll in terms of cases and lives lost, but also in its psychosocial effects. We assessed the psychosocial impacts of the COVID-19 pandemic in a large cohort of people w...

    Authors: Anne K. Monroe, Paige E. Kulie, Morgan E. Byrne, Brittany C. Wilbourn, Shannon K. Barth, Jenna B. Resnik, David M. Huebner, Michael A. Horberg, Amanda D. Castel and Alan E. Greenberg
    Citation: AIDS Research and Therapy 2023 20:27
    Content type: Research Published on:

  20. Prolonged exposure to HIV and anti-retroviral therapy (ART) has been linked with endothelial cell activation which subsequently predisposes people living with HIV (PLWH) to cardiovascular diseases. Serum bioma...

    Authors: Andrew Weil Semulimi, Charles Batte, Alice Bayiyana, Mariam Nakabuye, John Mukisa, Barbara Castelnuovo, Rosalind Parkes Ratanshi, Bruce J Kirenga and Isaac Ssinabulya
    Citation: AIDS Research and Therapy 2023 20:26
    Content type: Research Published on:

  21. Behavioral economic (BE) biases have been studied in the context of numerous health conditions, yet are understudied in the field of HIV prevention. This aim of this study was to quantify the prevalence of fou...

    Authors: Larissa Jennings Mayo-Wilson, Jessica Coleman Lewis, Sarah MacCarthy and Sebastian Linnemayr
    Citation: AIDS Research and Therapy 2023 20:25
    Content type: Research Published on:

  22. Expanding pre-exposure prophylaxis (PrEP) among transgender women in the United States is an important strategy to meet national HIV prevention goals, however self-reported use of PrEP is low in this group.

    Authors: Lisa M. Kuhns, Judy Perloff, Amy K. Johnson, Josie Lynne Paul, Kevin Pleasant, Kaiji Evans, Damian J. Denson, Deborah J. Gelaude, Patricia A. Bessler, Rose Diskin, Marbella Cervantes, Robert Garofalo and Anna L. Hotton
    Citation: AIDS Research and Therapy 2023 20:24
    Content type: Research Published on:

  24. Despite substantial antiretroviral therapy (ART) coverage among individuals with human immunodeficiency virus (HIV) infection in Tanzania, viral load suppression (VLS) among HIV-positive children receiving ART...

    Authors: Kihulya Mageda, Khamis Kulemba, Wilhelmina Olomi, Ntuli Kapologwe, Leornad Katalambula and Pammla Petrucka
    Citation: AIDS Research and Therapy 2023 20:22
    Content type: Research Published on:

  25. Women who are newly diagnosed with HIV infection during pregnancy may not be ready to immediately initiate lifelong antiretroviral therapy (ART; called Option B +) as is recommended. Lack of “readiness” drives...

    Authors: Mwangelwa Mubiana-Mbewe, Samuel Bosomprah, Rakesh Kumar Saroj, Jillian Kadota, Aybuke Koyuncu, Kusanthan Thankian and Michael J. Vinikoor
    Citation: AIDS Research and Therapy 2023 20:21
    Content type: Research Published on:

  26. We investigated the association between CYP2B6 polymorphisms and efavirenz drug resistance among women living with HIV who started on antiretroviral therapy during pregnancy and with high viremia during post-part...

    Authors: Allan Buzibye, Kara Wools-Kaloustian, Adeniyi Olagunju, Ellon Twinomuhwezi, Constantin Yiannoutsos, Andrew Owen, Megan Neary, Joshua Matovu, Grace Banturaki, Barbara Castelnuovo, Mohammed Lamorde, Saye Khoo, Catriona Waitt and Agnes Kiragga
    Citation: AIDS Research and Therapy 2023 20:20
    Content type: Brief Report Published on:

  27. Interruption in Treatment (IIT) is a challenge in HIV care and treatment programs in sub- Saharan Africa. High IIT among HIV adolescents has both individual and potential public health consequences including d...

    Authors: Expeditho L. Mtisi, Stella E. Mushy, Simon G. Mkawe, Antony Ndjovu, Eric Mboggo, Boniface S. Mlay, Frida Ngalesoni and Aisa Muya
    Citation: AIDS Research and Therapy 2023 20:19
    Content type: Research Published on:

  28. The Joint United Nations Programme on HIV/AIDS through the 95-95-95 target requires 95% of people living with HIV (PLHIV) on antiretroviral treatment (ART) to be virally suppressed. Viral Load (VL) non-suppres...

    Authors: Catherine Nakaye, Nelson Mukiza, Denis Mawanda, Hajira Kataike, Hellen Kaganzi, Grace Miriam Ahimbisibwe, Gerald Bright Businge, Raymonds Crespo Kyambadde and Rita Nakalega
    Citation: AIDS Research and Therapy 2023 20:18
    Content type: Research Published on:

  29. The long-term efficacy and safety of the 2-drug regimen dolutegravir (DTG) + lamivudine (3TC) and 3-drug single-tablet regimens recommended for antiretroviral therapy (ART)-naive people with HIV-1 (PWH) have y...

    Authors: Lee A. Evitt, Sakina Nanji, Richard A. Grove, Chinyere Okoli, Jean van Wyk and Sonya J. Snedecor
    Citation: AIDS Research and Therapy 2023 20:17
    Content type: Brief Report Published on:

  30. The usage of antiretroviral treatment (ART) has considerably decreased the morbidity and mortality related to HIV-1 (human immunodeficiency virus type 1) infection. However, ART is ineffective in eradicating t...

    Authors: Ruojing Bai, Chengcheng Song, Shiyun Lv, Linlin Chang, Wei Hua, Wenjia Weng, Hao Wu and Lili Dai
    Citation: AIDS Research and Therapy 2023 20:16
    Content type: Review Published on:

  31. Following reports of anti-retroviral therapy (ART) experienced Ugandan people living with HIV (PLHIV) presenting with diabetic ketoacidosis weeks to months following a switch to dolutegravir (DTG), the Uganda ...

    Authors: Frank Mulindwa, Barbara Castelnuovo, Nele Brusselaers, Robert Bollinger, Joshua Rhein, Mutebi Edrisa, Allan Buzibye, Willington Amutuhaire, George Yendewa, Sarah Nabaggala, Eva Laker Agnes Odongpiny, Ronald Kiguba, Aisha Nakawooza, Simon Dujanga, Martin Nabwana and Jean-Marc Schwarz
    Citation: AIDS Research and Therapy 2023 20:15
    Content type: Research Published on:

  32. HIV status disclosure among sexual partners is vital in HIV management. Community health workers (CHW) support HIV disclosure among adults living with HIV (ALHIV) in sexual relationships with disclosure diffic...

    Authors: Zubair Lukyamuzi, Bashir Ssuna, Ruth Nabisere Mirembe, Denis Mawanda, Paul Kinkumu, Christine Nalugo, Esther Adikin, Faridah Namisango, Rita Nakalega, Patience Atuhaire, Philippa Musoke and Lisa M. Butler
    Citation: AIDS Research and Therapy 2023 20:14
    Content type: Research Published on:

  33. Chronic inflammation has been described in people living with HIV (PLHIV) receiving antiretroviral therapy (ART) despite viral suppression. Inflammation associated non-communicable diseases, including atherosc...

    Authors: Sirawat Srichatrapimuk, Artit Wongsa, Somnuek Sungkanuparph, Sasisopin Kiertiburanakul, Boonrat Tassaneetrithep and Angsana Phuphuakrat
    Citation: AIDS Research and Therapy 2023 20:13
    Content type: Brief Report Published on:

  34. The orthopoxvirus causes the rare disease monkeypox, and underlying immune deficiencies might lead to worse outcomes. In this report, we described a rare case of monkeypox with an underlying immune deficiency ...

    Authors: Wooyoung Jang, Likhita Kandimalla, Sivagami Rajan, Rafael Abreu and Jamie Enrique Campos
    Citation: AIDS Research and Therapy 2023 20:12
    Content type: Case Report Published on:

  35. Men who have sex with men (MSM) is a key population for preventing HIV in China, yet pre-exposure prophylaxis (PrEP) is not widely accepted in this population. The objective of this manuscript was to assessed ...

    Authors: Yuan Guan, Tangkai Qi, Qibin Liao, Renfang Zhang, Jun Chen, Li Liu, Yinzhong Shen, Han Zhu, Qi Tang and Hongzhou Lu
    Citation: AIDS Research and Therapy 2023 20:11
    Content type: Research Published on:

  36. Older People Living with HIV (OPWH) combine both aging and HIV-infection features, resulting in ageism, stigma, social isolation, and low quality of life. This context brings up new challenges for healthcare p...

    Authors: Tomás Martín Grosso, Diana Hernández-Sánchez, Gordana Dragovic, Marta Vasylyev, María Saumoy, José Ramón Blanco, Diego García, Tetiana Koval, Cora Loste, Tendayi Westerhof, Bonaventura Clotet, Omar Sued, Pedro Cahn and Eugènia Negredo
    Citation: AIDS Research and Therapy 2023 20:10
    Content type: Research Published on:

  37. As use of dolutegravir (DTG) becomes more common in resource limited settings (RLS), the demand for integrase resistance testing is increasing. Affordable methods for genotyping all relevant HIV-1 pol genes (i.e....

    Authors: Sontaga Manyana, Melendhran Pillay, Lilishia Gounder, Aabida Khan, Pravi Moodley, Kogieleum Naidoo and Benjamin Chimukangara
    Citation: AIDS Research and Therapy 2023 20:9
    Content type: Research Published on:

  38. Doravirine has a unique resistance profile but how this profile might increase its usefulness beyond first-line therapy in persons with susceptible viruses has not been well studied. We sought to determine sce...

    Authors: Soo-Yon Rhee, Jonathan M. Schapiro, Francesco Saladini, Maurizio Zazzi, Saye Khoo and Robert W. Shafer
    Citation: AIDS Research and Therapy 2023 20:8
    Content type: Research Published on:

  39. Young men who have sex with men (MSM), are a key population at higher risk of HIV infection yet they are underrepresented in research. We conducted a bio-behavioral survey to estimate HIV prevalence and associ...

    Authors: Samuel Waweru Mwaniki, Peter Mwenda Kaberia, Peter Mwangi Mugo and Thesla Palanee-Phillips
    Citation: AIDS Research and Therapy 2023 20:7
    Content type: Research Published on:

  40. Psychological distress as measured by mental disorders like depression and anxiety is more prevalent in people living with HIV (PLHIV) than in the general population. However, the relationship between mental d...

    Authors: Nolusindiso Ncitakalo, Lovemore Nyasha Sigwadhi, Musawenkosi Mabaso, John Joska and Leickness Simbayi
    Citation: AIDS Research and Therapy 2023 20:6
    Content type: Research Published on:

  42. The COVID-19 epidemic and various control and mitigation measures to combat the widespread outbreak of the disease may affect other parts of health care systems. There is a concern that the COVID-19 pandemic c...

    Authors: SeyedAhmad SeyedAlinaghi, Pegah Mirzapour, Zahra Pashaei, Arian Afzalian, Marcarious M. Tantuoyir, Roghayeh Salmani, Seyed Farzad Maroufi, Parinaz Paranjkhoo, Seyede Parmis Maroufi, Hajar Badri, Sanaz Varshochi, Farzin Vahedi, Esmaeil Mehraeen and Omid Dadras
    Citation: AIDS Research and Therapy 2023 20:4
    Content type: Review Published on:

  43. Treatment management after repeated failure of antiretroviral therapy (ART) is difficult due to resistance and adherence challenges. For people who have failed non-nucleoside reverse transcriptase inhibitor-(N...

    Authors: Robert A. Salata, Beatriz Grinsztejn, Justin Ritz, Ann C. Collier, Evelyn Hogg, Robert Gross, Catherine Godfrey, Nagalingeswaran Kumarasamy, Cecilia Kanyama, John W. Mellors, Carole L. Wallis and Michael D. Hughes
    Citation: AIDS Research and Therapy 2023 20:3
    Content type: Research Published on:

  44. As children living with HIV transition from adolescence into adulthood, they face a considerable burden of psychiatric disorders (PDs) which may vary between the perinatally and behaviorally infected. The know...

    Authors: Anthony A. Olashore, Saeeda Paruk, Oluyemi O. Akanni and Bonginkosi Chiliza
    Citation: AIDS Research and Therapy 2023 20:2
    Content type: Research Published on:

  45. We assessed the virologic efficacy of switching to co-formulated elvitegravir, cobicistat, emtricitabine, tenofovir disoproxil fumarate (E/C/F/TDF) in patients with controlled HIV infection.

    Authors: Nathalie De Castro, Alexandre Brun, Pierre Sellier, Gwenn Hamet, Frédéric Mechaï, Valérie Garrait, Amélie Chabrol, Marie-Anne Bouldouyre, Eric Froguel, Didier Troisvallets, Pauline Caraux-Paz, Constance Delaugerre, Willy Rozenbaum and Jean-Michel Molina
    Citation: AIDS Research and Therapy 2023 20:1
    Content type: Research Published on:

  46. Incident syphilis leads to changes in plasma HIV-1 RNA and CD4 + T-cell level in people with HIV (PWH) with viraemia. Its effect in PWH on suppressive antiretroviral therapy (ART) is less clear.

    Authors: Phillip Chan, Tommy H. C. Tang, Ruby T. S. Kwong, Lawrence Chan, Helen S. Y. Chan, K. W. Lam, W. M. Ting, S. K. Yung, Emily C. T. Lam, M. Y. Chu, Wilson Lam, T. C. Wu, Patrick Li and M. P. Lee
    Citation: AIDS Research and Therapy 2022 19:69
    Content type: Brief Report Published on:

  47. Married women have a higher risk of contracting human immunodeficiency virus (HIV) or develop acquired immune deficiency syndrome (AIDS) than men. Knowledge of HIV/AIDS contributes significantly to describing ...

    Authors: Mohammad Nayeem Hasan, Sumi Tambuly, Kaniz Fatema Trisha, Md. Ashiqul Haque, Muhammad Abdul Baker Chowdhury and Md Jamal Uddin
    Citation: AIDS Research and Therapy 2022 19:68
    Content type: Research Published on:

  49. Inflammatory myofibroblastic tumor (IMT) is a rare disease that mostly occurs in younger people and is located in the lungs in the general population. We report a rare case of adrenal IMT in a patient with HIV...

    Authors: Mengmeng Zhang, Hui Liu, Zhiqiang Zhu, Yu Zhang, Yanyan Zhang and Xiaopeng Hu
    Citation: AIDS Research and Therapy 2022 19:66
    Content type: Case Report Published on:

  50. Substance use among people living with HIV is associated with poor health, social, and psychological outcomes. This study assessed the prevalence of substance use and associated factors among youth attending H...

    Authors: Zahra Morawej, Azan Nyundo, Ally Kinyaga, Veneranda Kirway, Sophia Kagoye, Andrew Turiho and Noeline Nakasujja
    Citation: AIDS Research and Therapy 2022 19:65
    Content type: Research Published on:

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AIDS Research and Therapy

ISSN: 1742-6405

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